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Chronic Systemic Inflammation – The Power of Food


(Part 2 of 4)

Chronic systemic inflammation occurs when the immune system stays activated for extended periods, attacking the body’s own tissues. The long list of diseases linked to chronic inflammation is startling: cardiovascular disease, stroke, obesity, type 2 diabetes, rheumatoid arthritis, cancer, asthma, chronic fatigue syndrome, fibromyalgia, skin conditions such as psoriasis, inflammatory bowel disease, autoimmune disorders such as lupus and multiple sclerosis, depression, anxiety, and even neurological diseases like Alzheimer’s and Parkinson’s.

Several factors contribute to chronic inflammation, including poor diet, stress, lack of physical activity, and environmental toxins. A diet high in processed, refined, and inflammatory foods can overwhelm the immune system, fueling inflammation. In this blog post, we’ll explore food choices that can help reduce chronic inflammation and improve your overall health.

1. Limit Refined Carbohydrates and Sugars

Refined carbohydrates and sugar spike blood sugar, triggering pro-inflammatory cytokines, insulin resistance, and metabolic dysfunction, all of which increase systemic inflammation. Examples include white bread, pastries, sugary snacks, soft drinks, and candy.

2. Avoid Trans Fats

Trans fats are synthetic fats created through hydrogenation and are known to increase inflammation by promoting inflammatory markers in the body. Found in many processed and fried foods, they should be completely avoided. Examples: Partially hydrogenated oils, margarine, and many packaged baked goods.

3. Limit Saturated Fats

Saturated fats can increase the levels of LDL cholesterol (the “bad” cholesterol), which is linked to inflammation and the development of atherosclerosis. Consuming large amounts of saturated fat may also increase the production of inflammatory markers in the body. Examples: Red meat, full-fat dairy products, and processed meats like luncheon meats, sausages and bacon.

4. Avoid Artificial Additives

Many artificial additives have been shown to disrupt gut bacteria and promote inflammatory responses:

  • Artificial Sweeteners (e.g.,aspartame, sucralose, saccharin, acesulfame potassium)
  • Monosodium Glutamate (MSG)
  • Artificial Food Colors (e.g., Red 40, Yellow 5, Yellow 6, Blue 1, Blue 2)
  • Preservatives
    • Sodium Benzoate -Commonly found in soda, pickles, and salad dressings, sodium benzoate has been associated with inflammation, particularly when combined with artificial food coloring.
    • Butylated Hydroxyanisole (BHA) and Butylated Hydroxytoluene (BHT) – Used to prevent rancidity in processed foods.
  • Propyl Gallate -Used in oils and processed meats.
  • Carrageenan – A thickening agent used in dairy products and plant-based milk alternatives.
  • Sulfites (e.g., sodium bisulfite, potassium bisulfite) – found in some dried fruits, wine, and some processed foods.
  • Potassium Bromate -Used to strengthen dough in baking.
  • Propylene Glycol – Often found in ice cream, salad dressings, and some packaged foods.
  • Artificial Flavor Enhancers (e.g., disodium inosinate, disodium guanylate) often used in conjunction with MSG.
  • High-Fructose Corn Syrup (HFCS) -While not necessarily an “artificial additive” in the traditional sense, HFCS is highly processed and has been linked to increased inflammation and insulin resistance.
  • Brominated Vegetable Oil (BVO) – Used in some citrus-flavored sodas and energy drinks.
5. Be Aware of Excess Omega-6 Fatty Acids

Omega-3 fatty acids (EPA and DHA) reduce inflammation and support heart health, brain function, and the immune system. Omega-6 fatty acids are also essential, but an excess, common in the Western diet, contributes to chronic inflammation and disease. The ideal omega-6 to omega-3 ratio is 1:1 to 2:1, but the Western diet often has a ratio of 15:1 or higher.

  • Omega-3 Sources: Fatty fish (tuna, salmon, sardines), chia seeds, flaxseeds, walnuts.
  • Avoid Omega-6 from Processed Foods: Chips, baked goods, fast food (containing soybean, sunflower, and corn oil).
  • Choose Natural Omega-6 Sources: Nuts, seeds, whole grains, legumes, tofu, soy products, eggs, avocados.
  • Choose Healthier Oils: Extra virgin olive oil, avocado oil, coconut oil.
6. Choose Organic and Non-GMO Foods When Possible

Organic and non-GMO foods helps reduce inflammation in several ways:

  • Fewer Pesticides and Chemicals: Organic foods are free from synthetic pesticides, which can disrupt hormone balance and immune function.
  • Higher Nutrient Density: Organic foods often contain more antioxidants, vitamins, and minerals that combat oxidative stress and inflammation.
  • No GMOs: Non-GMO foods may reduce inflammation, as some GMO proteins could trigger immune responses.
  • Better Fatty Acid Profile: Organic animal products, like grass-fed beef or pastured eggs, offer a healthier omega-3 to omega-6 ratio, reducing inflammation.
7. Choose Natural Foods

Eating the right foods and incorporating anti-inflammatory spices into your diet can significantly help reduce chronic inflammation:

  1. Beneficial Foods
    • Fatty Fish – Rich in omega-3 fatty acids, which have powerful anti-inflammatory effects. Examples: Salmon, mackerel, sardines, trout, herring, anchovies, albacore tuna (especially when fresh, not canned), swordfish, halibut, lake trout.
    • Leafy Greens – High in antioxidants and anti-inflammatory compounds. Examples: Spinach, kale, Swiss chard, arugula.
    • Cruciferous Vegetables – Rich in sulforaphane, a compound that reduces inflammation and supports detoxification. Examples: Broccoli, cauliflower, brussels sprouts, cabbage, bok choy.
    • Berries – Packed with antioxidants that help combat inflammation. Examples: Blueberries, strawberries, raspberries, blackberries.
    • Nuts and Seeds – Contain healthy fats and fiber that support anti-inflammatory processes. Examples: Walnuts, almonds, chia seeds, flaxseeds, and hemp seeds.
    • Tomatoes – High in lycopene, an antioxidant that helps lower inflammation, especially when cooked.
    • Beans and Legumes – High in fiber and plant-based protein, which help reduce inflammation markers in the body. Edamame also contains omega-3 fatty acids, particularly ALA (alpha-linolenic acid), which has anti-inflammatory properties. Examples: Lentils, chickpeas, black beans, kidney beans, and edamame.
    • Whole Grains – Rich in fiber and antioxidants that can reduce inflammation and support gut health. Examples: Oats, brown rice, quinoa, barley, and whole wheat.
    • Avocados – Contain heart-healthy monounsaturated fats and antioxidants like vitamin E that help reduce inflammation.
    • Citrus Fruits – High in vitamin C, which has antioxidant properties and helps reduce inflammation. Examples: Oranges, lemons, grapefruits, and limes.
    • Dark Chocolate – Especially varieties with 70% or higher cocoa content, rich in flavonoids, which reduce inflammation by lowering oxidative stress and inflammatory markers. Consume in moderation.
  2. Beneficial Spices –
    • Turmeric – Contains curcumin, a powerful anti-inflammatory compound. Best absorbed with black pepper.
    • Ginger – Known for its anti-inflammatory and antioxidant properties, ginger can be used fresh, in tea, or in cooking.
    • Cinnamon – Known for its anti-inflammatory and antioxidant properties, cinnamon can help reduce inflammation related to metabolic dysfunction and chronic diseases.
    • Garlic – Contains sulfur compounds that have potent anti-inflammatory effects.
  3. Healthy Oils –
    • Extra Virgin Olive Oil – Benefits: One of the best oils for reducing inflammation. The polyphenols in olive oil have been shown to have anti-inflammatory effects similar to ibuprofen. It’s great for drizzling on salads, roasting vegetables, or sautéing.
    • Avocado Oil – Benefits: Rich in heart-healthy monounsaturated fats and antioxidants that reduce inflammation. It also has a high smoke point, making it suitable for high-heat cooking methods like frying or grilling.
    • Coconut Oil – Benefits: While coconut oil is high in saturated fat, it contains medium-chain triglycerides (MCTs) and lauric acid, which have been shown to have antimicrobial and anti-inflammatory effects. It’s a great choice for cooking at moderate temperatures or baking.
8. Improve Gut Health

Gut health is crucial for managing chronic inflammation, as the gut microbiome regulates inflammation throughout the body. Disrupting its balance can trigger an overactive immune response and increase inflammation. How to improve your gut health:

  • Prebiotic Foods: Garlic, onions, leeks, asparagus, bananas.
  • Probiotic Foods: Yogurt, kefir, kimchi, sauerkraut, miso.
  • Increase Fiber: Whole grains, beans, and vegetables promote healthy gut bacteria.
  • Limit Processed Foods: These harm the gut microbiome and contribute to inflammation.
9. Be Aware Dairy May Cause Inflammation

Dairy can contribute to chronic inflammation in individuals with lactose or casein sensitivities. For people with lactose intolerance, consuming dairy can lead to digestive discomfort, which can trigger a cascade of inflammatory responses that affect the whole body. Additionally, casein and the saturated fats found in full-fat dairy products may stimulate the production of pro-inflammatory cytokines, leading to chronic inflammation over time. Reducing or eliminating dairy may help those with sensitivities reduce inflammation and improve health.

10. Limit Alcohol Consumption

Limiting alcohol consumption is an effective strategy to reduce chronic systemic inflammation, as excessive alcohol intake activates inflammatory pathways, increases pro-inflammatory cytokines, and disrupts gut health. Reducing or eliminating alcohol helps mitigate these effects, supporting overall health and reducing the risk of conditions like cardiovascular disease, liver disease, and arthritis.

Meal Ideas

Breakfast Ideas

  1. Berry Chia Pudding with Walnuts
    • Chia seeds, almond milk, mixed berries, walnuts, a drizzle of honey or maple syrup.
  2. Avocado Toast with Scrambled Eggs
    • Whole-grain toast, ripe avocado, eggs, a sprinkle of flaxseeds.
  3. Spinach Breakfast Bowl with Sweet Potato
    • Roasted sweet potatoes, sautéed spinach, poached egg, olive oil, flaxseeds.

Lunch or Dinner Ideas

  1. Grilled Salmon Salad with Olive Oil Dressing
  2. Chicken, vegetable, and Quinoa Bowl
  3. Fatty Fish of Choice and Roasted Vegetable Bowl
  4. Chicken and Avocado Salad with Lemon-Tahini Dressing
  5. Vegetable Stir-Fry with Tofu and Brown Rice
Conclusion

Chronic systemic inflammation is a root cause of many common diseases, from heart disease to neurological conditions. By making the right food choices, you can combat inflammation and take control of your health. Embrace the journey to a healthier, more vibrant you—small, gradual changes can yield significant benefits for your body and mind.

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